The Compounded Semaglutide Pricing Landscape
Compounded semaglutide has become one of the most searched healthcare topics in the country — and for good reason. At $146–$299/month, it's a fraction of brand-name Wegovy's $1,349 list price. But "compounded semaglutide" is not one product. Prices, formats, inclusions, and quality vary dramatically across providers.
We tracked pricing from 10+ telehealth providers to help you compare the real cost — not just the headline number on a Facebook ad.
Price Range
Compounded semaglutide ranges from $146 to $299/mo across major telehealth providers as of March 2026.
Provider Price Comparison Table
| Provider | Starting Price | Ongoing Price | Consult Fee | Format |
|---|---|---|---|---|
| Yucca Health | $146/mo | Varies (multi-mo commitment) | Included | Injectable |
| MEDVi | $179/mo | $299/mo | Included | Injectable + Oral |
| SHED | $199/mo | $199/mo flat | Included | Injectable, Drops, Lozenges |
| Synergy Rx | $200/mo | Varies by dose | Included | Injectable + Oral tablets |
| Hims | $199/mo | $199/mo (annual plan) | Included | Injectable |
| Henry Meds | $199/mo | $297–$397/mo by dose | Included | Injectable + Sublingual |
| Ivim Health | $150/mo (med only) | $150 + $75 membership | $75/mo membership | Injectable |
Watch Out: Hidden Cost Traps
The advertised price is rarely the full picture. Here are the most common ways telehealth providers obscure the true cost of compounded semaglutide:
The Membership Fee Trap
Some providers advertise a low medication price ($75–$150/month) but require a separate monthly membership fee ($50–$100). The "true monthly cost" is the sum of both. A $75/month medication with a $75/month membership is actually $150/month — twice the advertised price.
The Upfront Commitment Trap
Several providers offer their lowest price only if you commit to 6–12 months upfront, paid in full. If you quit after month 2 (common due to side effects), you've prepaid for months you won't use. Month-to-month pricing from these providers is often 30–50% higher.
The Dose Escalation Trap
Some providers quote pricing for the starting dose (0.25mg) but charge significantly more at therapeutic doses (1.0mg+). If your provider charges by dose tier, your month-6 price could be $100–$200/month higher than your month-1 price.
Format Comparison: Injectable vs. Oral vs. Drops
Injectable semaglutide is the standard format — a weekly subcutaneous injection, the same delivery method as brand-name Wegovy. It has the most clinical evidence and generally the most predictable absorption.
Sublingual drops and lozenges are alternatives for needle-averse patients. They dissolve under the tongue and are absorbed through the oral mucosa. However, there are no published clinical trials specifically evaluating these formats. Absorption rates may differ from injectable versions.
Compounded oral tablets are also available from some providers. Unlike the FDA-approved Wegovy pill (which uses patented SNAC absorption technology), compounded oral tablets use different formulations. Absorption and efficacy may vary.
Our Top Picks by Situation
Lowest Price: Yucca Health ($146/mo)
Yucca Health — From $146/mo
One of the lowest intro prices for compounded semaglutide. Tirzepatide available from $258/mo. Buy-now-pay-later options available.
Check Availability →Sponsored · Compounded medications are not FDA-approved.
Most Flexible: SHED ($199/mo)
SHED stands out for offering the widest range of medication formats — injectable, drops, and lozenges — plus both semaglutide and tirzepatide. The 10% weight-loss guarantee adds a layer of confidence, and FSA/HSA acceptance helps with costs.
SHED — From $199/mo
Compounded semaglutide and tirzepatide with a 10% weight-loss guarantee. Choose injectable, drops, or lozenges. FSA/HSA accepted.
Check Availability →Sponsored · Compounded medications are not FDA-approved.
Simplest Pricing: Synergy Rx ($200/mo)
Synergy Rx's all-inclusive model means no membership fees, no surprise charges for consultations or dose changes, and no shipping costs. What you see is what you pay. For patients who want predictable billing, it's hard to beat.
Synergy Rx — From $200/mo
All-inclusive compounded semaglutide. No hidden fees — consultation, medication, and shipping bundled into one price.
Check Availability →Sponsored · Compounded medications are not FDA-approved.
The Regulatory Picture
Compounded semaglutide exists in a shifting regulatory environment. The FDA resolved the semaglutide shortage in February 2025 and subsequently issued 30+ warning letters to telehealth companies in March 2026. Compounding is now limited to patients with documented medical needs (such as allergies or non-standard dosing requirements).
What this means for you: compounded semaglutide is still available, but access may become more restrictive over time. If you're considering it, discuss eligibility with your provider.
Compounded vs. Brand-Name: Which Should You Choose?
If the Wegovy pill at $149/month is within your budget and you prefer the assurance of FDA approval, that's now a very strong option — especially for new patients starting treatment.
If cost is the primary factor and you're comfortable with the regulatory nuances, compounded semaglutide from a reputable provider remains significantly cheaper at maintenance doses ($199–$250/mo vs. $349/mo for brand-name).
See all options compared on our master pricing table.